Yes in several ways. On the one hand, the marketplaces module makes it possible to exclude certain categories, and on the other hand, Sellermania makes it possible to exclude any product from the sale of one or more marketplaces in an ultra flexible way. Filters make it possible not to sell a particular product, such or such brand, supplier, category, price bracket, etc.
You have full control over these filters and can combine them with all kinds of rules, as fine as your imagination allows.